Both stimulate repair, but they work through different mechanisms, suit different people and are planned as different courses. A clear comparison.
What each one actually is
PRP uses your own blood. A small sample is drawn, spun in a centrifuge to concentrate the platelets, and the plasma is then introduced to the treatment area, where the platelets release growth factors that prompt repair.
Exosome therapy uses ASCE+ exosomes — tiny messaging vesicles that carry signals to your skin cells, encouraging collagen and elastin production, calming inflammation and supporting the barrier. Nothing is taken from you; the product is applied after channels are created in the skin.
Practical differences in the appointment
PRP takes around an hour and twenty minutes because of the blood draw and processing, and is not suitable if you are needle-averse or have certain blood conditions. Exosome therapy takes about an hour with no blood draw.
Downtime is short for both — usually redness on the day — but PRP can leave small pinpoint marks or brief swelling depending on the technique used.
Courses and timing
PRP is recommended as three treatments a month apart. Exosome therapy is planned as five sessions at two to four week intervals. Both build gradually, with the clearest change from around six to twelve weeks.
Both are also used for the scalp. The exosome hair protocol combines exosomes with growth factors, biotin and copper peptides; PRP is the longer-established option for thinning hair.
How the choice is made
It depends on your skin, your health history, whether you are comfortable with a blood draw, and how the treatment fits alongside microneedling or peels already in your plan. Neither is a substitute for surgery, and neither will correct significant laxity.
That decision is made face to face, not online. If a treatment will not achieve what you are hoping for, you will be told so before you book.